Davide Viviano, Kaspar Wuthrich, Paul Niehaus
arXiv 27 Apr 2021 · General Economics · publishedThe Review of Economic Studies (2026) · 11 citations (OpenAlex)
arXiv:2104.13367 · PDF · DOI · OpenAlex · Extracted main text
Multiple hypothesis testing practices vary widely, without consensus on which are appropriate when. This paper provides an economic foundation for these practices designed to capture leading examples, such as regulatory approval on the basis of clinical trials. In studies of multiple treatments or sub-populations, adjustments may be appropriate depending on scale economies in the research production function, with control of classical notions of compound errors emerging in some but not all cases. In studies with multiple outcomes, indexing is appropriate and adjustments to test levels may be appropriate if the intended audience is heterogeneous. Data on actual costs in the drug approval process suggest both that some adjustment is warranted in that setting and that standard procedures may be overly conservative.
appendix boundary found by appendix_command · 52% of the source is main text. Read the extracted text to check this.
The works this paper leans on most, across its whole bibliography — not restricted to papers in our corpus. Ranked by composite intensity, which combines how often a work is mentioned, how many sections mention it, and how much of that falls in the main text rather than the appendix.
| Reference | Intensity | Mentions | Sections | Main text | |
|---|---|---|---|---|---|
| 1 | Banerjee, A. V., S. Chassang, S. Montero, and E. Snowberg (2020) A theory of experimenters: Robustness, randomization, and balance | 0.874 | 5 | 2 | 100% |
| 2 | Lehmann, E. L. and J. P. Romano (2005) Testing statistical hypotheses | 0.843 | 4 | 3 | 75% |
| 3 | Sidák, Z (1968) On multivariate normal probabilities of rectangles: their dependence on correlations | 0.843 | 4 | 3 | 75% |
| 4 | Gilboa, I. and D. Schmeidler (1989) Maxmin expected utility with non-unique prior | 0.811 | 4 | 2 | 100% |
| 5 | Tetenov, A (2016) An economic theory of statistical testing | 0.794 | 14 | 7 | 50% |
| 6 | Romano, J. P., A. Shaikh, and M. Wolf (2011) Consonance and the closure method in multiple testing | 0.737 | 3 | 3 | 67% |
| 7 | Tetenov, A (2012) Statistical treatment choice based on asymmetric minimax regret criteria | 0.737 | 3 | 2 | 100% |
| 8 | Viviano, D., K. Wuthrich, and P. Niehaus (2025) A model of multiple hypothesis testing self | 0.644 | 2 | 2 | 100% |
| 9 | Efron, B (2008) Microarrays, empirical bayes and the two-groups model | 0.644 | 2 | 2 | 100% |
| 10 | Food and Drug Administration (2022, October) (2022) Multiple endpoints in clinical trials guidance for industry | 0.644 | 2 | 2 | 100% |
Showing the top 10 of 54 scored citations.
arXiv econ.EM papers that cite this one, ranked by how heavily they lean on it.
| Citing paper | Intensity | Mentions | Sections | |
|---|---|---|---|---|
| 1 | Designing persuasive experiments | 0.511 | 2 | 1 |
| 2 | 2412.16452 | 0.405 | 1 | 1 |
| 3 | Certified Decisions | 0.405 | 1 | 1 |
| 4 | Publication Design with Incentives in Mind | 0.405 | 1 | 1 |
| 5 | 2510.21178 | 0.405 | 1 | 1 |