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Efficient Difference-in-Differences and Event Study Estimators

Xiaohong Chen, Pedro H. C. Sant'Anna, Haitian Xie

arXiv 21 Jun 2025 · Econometrics

arXiv:2506.17729 · PDF · Extracted main text

Abstract

This paper investigates efficient Difference-in-Differences (DiD) and Event Study (ES) estimation using short panel data sets within the heterogeneous treatment effect framework, free from parametric functional form assumptions and allowing for variation in treatment timing. We provide an equivalent characterization of the DiD potential outcome model using sequential conditional moment restrictions on observables, which shows that the DiD identification assumptions typically imply nonparametric overidentification restrictions. We derive the semiparametric efficient influence function (EIF) in closed form for DiD and ES causal parameters under commonly imposed parallel trends assumptions. The EIF is automatically Neyman orthogonal and yields the smallest variance among all asymptotically normal, regular estimators of the DiD and ES parameters. Leveraging the EIF, we propose simple-to-compute efficient estimators. Our results highlight how to optimally explore different pre-treatment periods and comparison groups to obtain the tightest (asymptotic) confidence intervals, offering practical tools for improving inference in modern DiD and ES applications even in small samples. Calibrated simulations and an empirical application demonstrate substantial precision gains of our efficient estimators in finite samples.

Citation extraction

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Most heavily cited references

The works this paper leans on most, across its whole bibliography — not restricted to papers in our corpus. Ranked by composite intensity, which combines how often a work is mentioned, how many sections mention it, and how much of that falls in the main text rather than the appendix.

ReferenceIntensityMentionsSectionsMain text
1Arkhangelsky, Athey, Hirshberg, Imbens and Wager (2021) Synthetic Difference-in-Differences1.000244100%
2Sun and Abraham (2021) Estimating dynamic treatment effects in event studies with heterogeneous treatment effects1.000144100%
3Callaway and Sant’Anna (2021) Difference-in-Differences with multiple time periods1.000137100%
4Baker, Larcker and Wang (2022) How much should we trust staggered difference-in-differences estimates?1.000103100%
5Wooldridge (2021) Two-Way Fixed Effects, the Two-Way Mundlak Regression, and Difference-in-Differences Estimators1.00095100%
6Gardner (2021) Two-stage differences in differences1.00064100%
7de Chaisemartin and D'Haultfœuille (2020) Two-Way Fixed Effects Estimators with Heterogeneous Treatment Effects0.96510690%
8Borusyak, Jaravel and Spiess (2024) Revisiting Event Study Designs: Robust and Efficient Estimation0.94613685%
9Dobkin, Finkelstein, Kluender and Notowidigdo (2018) The economic consequences of hospital admissions0.87482100%
10Chen and Santos (2018) Overidentification in Regular Models0.8435460%

Showing the top 10 of 60 scored citations.

Cited by, within the corpus

arXiv econ.EM papers that cite this one, ranked by how heavily they lean on it.

Citing paperIntensityMentionsSections
1Doubly Robust Instrumented Difference-in-Differences0.73732
2Difference-in-Differences Designs: A Practitioner's Guide0.69361
3Doubly Robust Estimation of Treatment Effects in Staggered Difference-in-Differences with Time-Varying Covariates0.64422
4Instrumented Difference-in-Differences with Heterogeneous Treatment Effects0.51121
5Synthetic Parallel Trends0.51121
6Design-Based Variance Estimation for Modern Heterogeneity-Robust Difference-in-Differences Estimators0.51122
7Difference-in-Differences Meets Synthetic Control: Doubly Robust Identification and Estimation0.40511
8Better Understanding Triple Differences Estimators0.40511
9Triply Robust Panel Estimators0.40511
10Cohort-Anchored Robust Inference for Event-Study with Staggered Adoption0.40511