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Empirical Bayes for compound adaptive experiments

Karun Adusumilli, Jiaying Gu, Junfan Tao

arXiv 15 Sep 2026 · Econometrics

arXiv:2609.17158 · PDF · Extracted main text

Abstract

We investigate Empirical Bayes (EB) methods in the context of compound adaptive experiments, where the arm distribution in each experiment follows a normal distribution with an unknown mean that we seek to estimate. There are two main EB strategies: $g$-modeling, which estimates the prior by maximizing the marginal likelihood, and $f$-modeling, which derives posterior means directly from the empirical distribution of the observations. We show that $g$-modeling continues to be a valid EB procedure even when it incorrectly assumes that data are collected exogenously; its validity does not depend on the particular sampling algorithm or on whether sample sizes are endogenous. In practice, one can apply standard $g$-modeling techniques by acting as though the data were exogenously sampled. We extend regret guarantees from exogenous sampling to adaptively generated data. By contrast, naively applying the Tweedie formula based on the marginal density of the observed data, as in standard $f$-modeling, can produce biased rules under adaptive sampling. We corroborate the robustness of $g$-modeling through simulations with widely used adaptive algorithms and demonstrate its applicability using a real-world dataset consisting of multiple sequential experiments.

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39
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Most heavily cited references

The works this paper leans on most, across its whole bibliography — not restricted to papers in our corpus. Ranked by composite intensity, which combines how often a work is mentioned, how many sections mention it, and how much of that falls in the main text rather than the appendix.

ReferenceIntensityMentionsSectionsMain text
1Chen, Jiafeng (2026) Empirical Bayes when estimation precision predicts parameters1.00054100%
2Jiang, Wenhua (2020) On General Maximum Likelihood Empirical Bayes Estimation of Heteroscedastic IID Normal Means0.9619389%
3Jiang, Wenhua and Zhang, Cun-Hui (2009) General Maximum Likelihood Empirical Bayes Estimation of Normal Means0.87462100%
4Efron, Bradley (2012) Large-Scale Inference: Empirical Bayes Methods for Estimation, Testing, and Prediction0.73732100%
5Wassmer, Gernot and Brannath, Werner (2016) Group Sequential and Confirmatory Adaptive Designs in Clinical Trials0.73732100%
6Soloff, Jake A and Guntuboyina, Adityanand and Sen, Bodhisattva (2025) Multivariate, Heteroscedastic Empirical Bayes via Nonparametric Maximum Likelihood0.67513431%
7Adusumilli, Karun (2020) Unobserved Heterogeneity, Grouped Random Effects and the EAMP Algorithm self0.64422100%
8Karun Adusumilli (2025) Risk and Optimal Policies in Bandit Experiments self0.64422100%
9Koenker, Roger and Mizera, Ivan (2014) Convex Optimization, Shape Constraints, Compound Decisions, and Empirical Bayes Rules0.64422100%
10Liu, CH and Cardoso, Ângelo and Couturier, Paul and McCoy, Emma J (2021) Datasets for Online Controlled Experiments0.64422100%

Showing the top 10 of 40 scored citations.