← All authors Edwin R. van den Heuvel Eindhoven University of Technology (per OpenAlex) · ORCID · OpenAlex
80 papers in scope · 80 published · 1 on the econ.EM arXiv · 1,920 citations · h-index 19 (over the papers listed here)
Papers Show only papers in our arXiv econ.EM corpus (1 of 80)
Moment estimators for a three-parameter family of spatial Poisson models
published 2026 · Spatial Statistics
with I.L. van den Heuvel, Marta Regis, Zhuozhao Zhan, Maurits Kaptein
The Poisson CUSUM Chart for Monitoring Small Counts: Addressing the Estimation Uncertainty
published 2026 · Biometrical Journal
with Stan Heidema, Ivo V. Stoepker, Ralph Huits
Optimizing clinical scientific research: the cohort intervention random sampling study with historical controls
published 2025 · Journal of Comparative Effectiveness Research · 2 citations
with Nadine D de Klerk, Phebe B Q Berben, Myrthe van der Ven, Annemarie Fransen, M. Beatrijs van der Hout-van der Jagt, S. Guid Oei, Judith O. E. H. van Laar
A comparison of semi-parametric statistical modeling approaches to dynamic classification of irregularly and sparsely sampled curves
published 2025 · Statistical Methods in Medical Research
with Ruben Deneer, Zhuozhao Zhan, Astrid G.M. van Boxtel, Arjen-Kars Boer, N.A.W. van Riel, Volkher Scharnhorst
Latent-class trajectory modeling with a heterogeneous mean-variance relation
published 2025 · Computational Statistics & Data Analysis · 1 citations
with Niek Den Teuling, Francesco Ungolo, Steffen Pauws
Beyond conditional averages: Estimating the individual causal effect distribution
published 2025 · Journal of Causal Inference · 1 citations · first circulated 2022
Bias of the additive hazard model in the presence of causal effect heterogeneity
published 2024 · Lifetime Data Analysis · 1 citations · first circulated 2022
Simulation models for aggregated data meta-analysis: Evaluation of pooling effect sizes and publication biases
published 2024 · Statistical Methods in Medical Research · 3 citations · first circulated 2020
with Osama Almalik, Zhuozhao Zhan
A Dirichlet process mixture regression model for the analysis of competing risk events
published 2024 · Insurance Mathematics and Economics · 4 citations · first circulated 2023
with Francesco Ungolo
A variable clustering approach for overdispersed high-dimensional count data using a copula-based mixture model
published 2024 · Communications in Statistics - Simulation and Computation · 1 citations
with Alberto Brini, Abu Manju
The built-in selection bias of hazard ratios formalized using structural causal models
published 2024 · Lifetime Data Analysis · 7 citations · first circulated 2022
Introducing exceptional growth mining—Analyzing the impact of soil characteristics on on-farm crop growth and yield variability
published 2024 · PLoS ONE · 3 citations
with Puck J.A.M. Mulders, Pytrik Reidsma, Wouter Duivesteijn
published 2023 · Epidemiology · 4 citations · first circulated 2022
Editorial statistics
published 2023 · Statistica Neerlandica
with Veronica Vinciotti, Ernst C. Wit
Missing Data Imputation with High-Dimensional Data
published 2023 · The American Statistician · 9 citations
with Alberto Brini
Kendall’s tau estimator for bivariate zero-inflated count data
published 2023 · Statistics & Probability Letters · 2 citations · first circulated 2022
with Elisa Perrone, Zhuozhao Zhan
Sharp inequalities of Bienaymé–Chebyshev and Gauß type for possibly asymmetric intervals around the mean
published 2023 · Test · 8 citations · first circulated 2022
with Roxana A. Ion, Chris A. J. Klaassen
Binary disease prediction using tail quantiles of the distribution of continuous biomarkers
published 2022 · Journal of nonparametric statistics · 2 citations · first circulated 2021
with Michiel H. J. Paus, Marc J. M. Meddens
Comparison of analysis methods and design choices for treatment-by-period interaction in unidirectional switch designs: a simulation study
published 2022 · BMC Medical Research Methodology · 1 citations
with Zhuozhao Zhan, Geertruida H. de Bock
Copas’ method is sensitive to different mechanisms of publication bias
published 2022 · Statistics & Probability Letters · 1 citations · first circulated 2020
with Osama Almalik, Zhuozhao Zhan
The electrical heart axis in fetuses with congenital heart disease, measured with non-invasive fetal electrocardiography
published 2022 · PLoS ONE · 2 citations
with Lore Noben, Carlijn Lempersz, Zhuozhao Zhan, Frank P.H.A. Vandenbussche, A. Coumans, Monique C. Haak, Rik Vullings, S. Guid Oei, Sally-Ann B. Clur, Judith O. E. H. van Laar
Anomaly Detection for a Large Number of Streams: A Permutation-Based Higher Criticism Approach
published 2022 · Journal of the American Statistical Association · 3 citations · first circulated 2020
with Ivo V. Stoepker, Rui M. Castro, Ery Arias-Castro, Rui Castro
Non-inferiority testing for qualitative microbiological methods:Assessing and improving the approach in USP
published 2022 · Journal of Biopharmaceutical Statistics · 3 citations
with Pieta C. IJzerman-Boon, Md Abu Manju
A normal-probit-binomial model for the analysis of repeated sum scores from multi-item questionnaires
published 2022 · Communications in Statistics - Simulation and Computation
with Nazanin Nooraee, Geert Molenberghs, Johan Ormel
Jointly pooling aggregated effect sizes and their standard errors from studies with continuous clinical outcomes
published 2022 · Biometrical Journal · 1 citations
with Osama Almalik, Zhuozhao Zhan
D-Optimal Designs for the Mitscherlich Non-Linear Regression Function
published 2022 · Mathematical Methods of Statistics · 2 citations · first circulated 2021
with Maliheh Heidari, Md Abu Manju, Pieta C. IJzerman-Boon
Inference on latent factor models for informative censoring
published 2022 · Statistical Methods in Medical Research · 8 citations
with Francesco Ungolo
The electrical heart axis of the fetus between 18 and 24 weeks of gestation: A cohort study
published 2021 · PLoS ONE · 9 citations
with Carlijn Lempersz, Lore Noben, Sally-Ann B. Clur, Zhouzhao Zhan, Monique C. Haak, S. Guid Oei, Rik Vullings, Judith O. E. H. van Laar
A latent-class heteroskedastic hurdle trajectory model: patterns of adherence in obstructive sleep apnea patients on CPAP therapy
published 2021 · BMC Medical Research Methodology · 6 citations
with Niek Den Teuling, Mark S. Aloia, Steffen Pauws
Myths About Linear and Monotonic Associations: Pearson’s r , Spearman’s ρ , and Kendall’s τ
published 2021 · The American Statistician · 166 citations
with Zhuozhao Zhan
A comparison of statistical methods for age-specific reference values of discrete scales
published 2021 · Communications in Statistics - Simulation and Computation · 3 citations
with Zhuozhao Zhan, Sacha la Bastide-van Gemert, M. Wiersum, Kirsten R. Heineman, Mijna Hadders-Algra
Improved One-Class Modeling of High-Dimensional Metabolomics Data via Eigenvalue-Shrinkage
published 2021 · Metabolites · 4 citations
with Alberto Brini, Vahe Avagyan, Ric C. H. de Vos, Jack H. Vossen, Jasper Engel
Random autoregressive models: A structured overview
published 2021 · Econometric Reviews · 37 citations
with Marta Regis, Paulo Serra, P.J. de Andrade Serra
Interevent-time distribution and aftershock frequency in non-stationary induced seismicity
published 2021 · Scientific Reports · 20 citations
with R. Post, M. A. J. Michels, Jean-Paul Ampuero, Thibault Candela, Peter A. Fokker, Jan-Diederik van Wees, Remco van der Hofstad
A comparison of methods for clustering longitudinal data with slowly changing trends
published 2021 · Communications in Statistics - Simulation and Computation · 48 citations
with Niek Den Teuling, Steffen Pauws
Performance measures of discrete and continuous time‐between‐events control charts
published 2020 · Quality and Reliability Engineering International · 12 citations
with Caterina Rizzo, Swee-Teng Chin, A. Di Bucchianico
Optimal unidirectional switch designs” by Zhuozhao Zhan, Geertruida H. de Bock, and Edwin R. van den Heuvel
published 2020 · Statistics in Medicine
with Zhuozhao Zhan
A bivariate zero-inflated Poisson control chart: Comments and corrections on earlier results
published 2020 · Communication in Statistics-Theory and Methods · 5 citations
with Stephan A. W. van Driel, Zhuozhao Zhan
Individual and population level impact of chronic conditions on functional disability in older adults
published 2020 · PLoS ONE · 76 citations
with Parminder Raina, Anne Gilsing, Alexandra Mayhew, Nazmul Sohel, Lauren E. Griffith
The t linear mixed model: model formulation, identifiability and estimation
published 2019 · Communications in Statistics - Simulation and Computation · 4 citations
with Marta Regis, Alberto Brini, Nazanin Nooraee, Reinder Haakma
Latent variable models for harmonization of test scores: A case study on memory
published 2019 · Biometrical Journal · 8 citations
with Lauren E. Griffith, Nazmul Sohel, Isabel Fortier, Graciela Muñiz-Terrera, Parminder Raina
Strategies for handling missing data in longitudinal studies with questionnaires
published 2018 · Journal of Statistical Computation and Simulation · 29 citations
with Nazanin Nooraee, Geert Molenberghs, Johan Ormel
Optimal unidirectional switch designs
published 2018 · Statistics in Medicine · 10 citations
with Zhuozhao Zhan, Geertruida H. de Bock
A preference-based item response theory model to measure health: concept and mathematics of the multi-attribute preference response model
published 2018 · BMC Medical Research Methodology · 51 citations
with Karin Groothuis-Oudshoorn, Paul F. M. Krabbe
A comparison of spiking experiments to estimate the detection proportion of qualitative microbiological methods
published 2018 · Journal of Biopharmaceutical Statistics · 4 citations
with Md Abu Manju, Pieta C. IJzerman-Boon
Equivalence testing for similarity in bioassays using bioequivalence criteria on the relative bioactivity
published 2017 · Pharmaceutical Statistics · 1 citations
with Corine Baljé-Volkers, Thembile Mzolo, Erik Talens, Pieta C. IJzerman-Boon
Psychological effects of the intensified follow-up of the CEAwatch trial after treatment for colorectal cancer
published 2017 · PLoS ONE · 8 citations
with Zhuozhao Zhan, C Verberne, I Grossmann, Adelita V. Ranchor, Theo Wiggers, Geertruida H. de Bock
Statistical methods for unidirectional switch designs: Past, present, and future
published 2017 · Statistical Methods in Medical Research · 11 citations
with Zhuozhao Zhan, Geertruida H. de Bock
An introduction to multiplicity issues in clinical trials: the what, why, when and how
published 2016 · International Journal of Epidemiology · 382 citations
with Guowei Li, Monica Taljaard, Mitchell Levine, Deborah J. Cook, George A. Wells, P.J. Devereaux, Lehana Thabane
Comparison of Standardization Methods for the Harmonization of Phenotype Data: An Application to Cognitive Measures
published 2016 · American Journal of Epidemiology · 26 citations
with Lauren E. Griffith, Parminder Raina, Isabel Fortier, Nazmul Sohel, Scott M. Hofer, Hélène Payette, Christina Wolfson, Sylvie Belleville, Meghan Kenny, Dany Doiron
The analysis of terminal endpoint events in stepped wedge designs
published 2016 · Statistics in Medicine · 10 citations
with Zhuozhao Zhan, Geertruida H. de Bock, Theo Wiggers
Discussion of “Modern measurement, probability, and statistics: Some generalities and multivariate illustrations”
published 2016 · Quality Engineering
An Approximate Marginal Logistic Distribution for the Analysis of Longitudinal Ordinal Data
published 2015 · Biometrics · 6 citations
with Nazanin Nooraee, Fentaw Abegaz, Johan Ormel, Ernst C. Wit
Medication Errors in Vietnamese Hospitals: Prevalence, Potential Outcome and Associated Factors
published 2015 · PLoS ONE · 46 citations
with Huong-Thao Nguyen, Tuan-Dung Nguyen, Flora M. Haaijer-Ruskamp, Katja Taxis
Do individuals with and without depression value depression differently? And if so, why?
published 2015 · Quality of Life Research · 20 citations
with Katerina Papageorgiou, Karin M. Vermeulen, Maya J. Schroevers, Anne M. Stiggelbout, Erik Buskens, Paul F. M. Krabbe, Adelita V. Ranchor
Confidence Intervals for Intraclass Correlation Coefficients in a Nonlinear Dose–Response Meta-Analysis
published 2015 · Biometrics · 6 citations
with Nino Demetrashvili
Statistical Process Control Methods for Monitoring In-House Reference Standards
published 2015 · Statistics in Biopharmaceutical Research · 1 citations
with Thembile Mzolo, Goele Goris, Erik Talens, A. Di Bucchianico
Validation of qualitative microbiological test methods
published 2014 · Pharmaceutical Statistics · 7 citations
with Pieta C. IJzerman-Boon
A stepped wedge design for testing an effect of intranasal insulin on cognitive development of children with Phelan-McDermid syndrome: A comparison of different designs
published 2014 · Statistical Methods in Medical Research · 9 citations
with Renée J. Zwanenburg, Conny MA van Ravenswaaij-Arts
Combined Statistical Analyses for Long-Term Stability Data with Multiple Storage Conditions: A Simulation Study
published 2014 · Journal of Biopharmaceutical Statistics · 6 citations
with Osama Almalik, Michiel B. Nijhuis
GEE for longitudinal ordinal data: Comparing R-geepack, R-multgee, R-repolr, SAS-GENMOD, SPSS-GENLIN
published 2014 · Computational Statistics & Data Analysis · 40 citations
with Nazanin Nooraee, Geert Molenberghs
Confidence intervals for intraclass correlation coefficients in variance components models
published 2014 · Statistical Methods in Medical Research · 35 citations
with Nino Demetrashvili, Ernst C. Wit
Skin Autofluorescence, a Non-Invasive Marker for AGE Accumulation, Is Associated with the Degree of Atherosclerosis
published 2013 · PLoS ONE · 74 citations
with Martijn A. M. den Dekker, M. Zwiers, Lisanne C. de Vos, Andries J. Smit, Clark J. Zeebregts, Matthijs Oudkerk, Rozemarijn Vliegenthart, Joop D. Lefrandt, Douwe J. Mulder
Causal inference algorithms can be useful in life course epidemiology
published 2013 · Journal of Clinical Epidemiology · 19 citations
with Sacha la Bastide-van Gemert, Ronald P. Stolk, V. Fidler
A comparison of statistical methods for combining relative bioactivities from parallel line bioassays
published 2013 · Pharmaceutical Statistics · 5 citations
with Thembile Mzolo, M. Hendriks
Exploring causal hypotheses: breaking with long‐standing research traditions
published 2013 · Developmental Medicine & Child Neurology · 13 citations
with Sacha la Bastide-van Gemert
‘All models are wrong...’: an introduction to model uncertainty
published 2012 · Statistica Neerlandica · 320 citations
with Ernst C. Wit, Jan-Willem Romeijn
Adhesion Forces and Coaggregation between Vaginal Staphylococci and Lactobacilli
published 2012 · PLoS ONE · 106 citations
with Jessica A. Younes, Henny C. van der Mei, Henk J. Busscher, Gregor Reid
Statistical Analysis for Long-term Stability Studies with Multiple Storage Conditions
published 2011 · Drug Information Journal · 4 citations
with Osama Almalik, Michiel B. Nijhuis, Edward I. Warner
A Comparison of Estimation Methods on the Coverage Probability of Satterthwaite Confidence Intervals for Assay Precision with Unbalanced Data
published 2010 · Communications in Statistics - Simulation and Computation · 14 citations
Closed-Form Confidence Intervals on Measures of Precision for An Interlaboratory Study
published 2006 · Journal of Biopharmaceutical Statistics · 11 citations
with Michiel B. Nijhuis
A Comparison of Methods for the Evaluation of Binary Measurement Systems
published 2005 · Quality Engineering · 35 citations
with Wessel N. van Wieringen
Evaluation of an Affymetrix High‐density Oligonucleotide Microarray Platform as a Measurement System
published 2005 · Quality and Reliability Engineering International · 1 citations
with Geert Geeven, Susanne Bauerschmidt, Jan Polman
Capability Indices and the Proportion of Nonconforming Items
published 2003 · Quality Engineering · 8 citations
with Roxana A. Ion
Evaluation of Measurement Systems with a Small Number of Observers
published 2002 · Quality Engineering · 9 citations
with Albert Trip
Comparing Nonmanufacturing with Traditional Applications of Six Sigma
published 2002 · Quality Engineering · 91 citations
with Ronald J. M. M. Does, Jeroen de Mast, Søren Bisgaard
Steps and strategies in process improvement
published 2000 · Quality and Reliability Engineering International · 33 citations
with Jeroen de Mast, W.A.J. Schippers, Ronald J. M. M. Does
Bayes Convolution
published 1999 · International Statistical Review
with Chris A. J. Klaassen
Bayes Convolution
published 1999 · International Statistical Review
with Chris A. J. Klaassen
Spread, Estimators and Nuisance Parameters
published 1997 · Bernoulli · 2 citations
with Chris A. J. Klaassen
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